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The Cyclin C-CDK8/19 Mediator kinase module controls PRCC-TFE3 driven senescence in renal epithelium and tumorigenesis in TFE3-RCC.

Kuroda S, Funasaki S, Nishizawa H, Schmidt LS, Kurahashi R, Ito T, Arima Y, Tanaka M, Kitada A, James AM, Hasumi H, Jikuya R, Makiyama K, Kurotaki D, Minami T, Difilippantonio S, Linehan WM, Oike Y, Sawa T, Tanaka Y, Suda T, Yokokawa R, Nakamura T, Baba M, Kamba T.

Neoplasia. 2026 May;75:101296. doi: 10.1016/j.neo.2026.101296. Epub 2026 Mar 16. PMID: 41843980

 

Circulating Tumor DNA Genomic Profiling in ²²³Ra-Treated Metastatic Castration-Resistant Prostate Cancer: The KYUCOG-1901 Study.

Shiota M, Fujiwara M, Sumiyoshi T, Enokida H, Kamba T, Igawa T, Masumori N, Uemura H, Kamoto T, Higashijima K, Mitsunari K, Uemura H, Kobayashi T, Akamatsu S, Tokunaga S, Isoda T, Ishigami K, Eto M.

J Nucl Med. 2026 Apr 16:jnumed.126.272073. doi: 10.2967/jnumed.126.272073. Online ahead of print. PMID: 41991340

 

Impact of treatment volume on outcomes for patients with penile cancer at relatively low-volume centers in Japan.

Murakami Y, Yamaguchi T, Goya M, Higashijima K, Tobu S, Sato R, Tatarano S, Mukai S, Uemura KI, Tatsugami K, Tsubouchi K, Shida Y, Ishii T, Sakai H, Matsuoka H, Haga N, Eto M, Igawa T, Kamoto T, Enokida H, Shin T, Noguchi M, Fujimoto N, Saito S, Kamba T.

Jpn J Clin Oncol. 2026 Apr 30:hyag070. doi: 10.1093/jjco/hyag070. Online ahead of print. PMID: 42059484

 

Comprehensive analysis of oncological outcomes of radical cystectomy for non-muscle invasive bladder cancer.

Sano T, Taoka R, Miki J, Saito R, Fukuokaya W, Matsui Y, Hatakeyama S, Kawahara T, Matsuda A, Kawai T, Kato M, Sazuka T, Urabe F, Kashima S, Naito H, Murakami Y, Miyake M, Daizumoto K, Matsushita Y, Hayashi T, Inokuchi J, Sugino Y, Shiga K, Yamaguchi N, Yamamoto S, Yasue K, Abe T, Nakanishi S, Hashine K, Fujii M, Nishihara K, Matsumoto H, Tatarano S, Wada K, Sekito S, Maruyama R, Nishiyama N, Nishiyama H, Kitamura H, Kobayashi T; Japan Urological Oncology Group.

Sci Rep. 2026 Apr 5. doi: 10.1038/s41598-026-46649-w. Online ahead of print. PMID: 41936674

 

Avelumab maintenance therapy for advanced urothelial carcinoma: subgroup analyses by characteristics of first-line platinum-based chemotherapy from a real-world chart review study in Japan (JAVEMACS).

Endo Y, Kitamura H, Shirotake S, Ikeda M, Yonemori K, Kawamura N, Fujihara A, Shimizu F, Fujimoto K, Nakagawa T, Hatakeyama S, Nishihara K, Ikarashi D, Masumori N, Naito S, Fujita K, Hara T, Miura N, Negishi T, Yatsuda J, Kobayashi M, Taoka R, Furukawa J, Shono M, Kobayashi T, Kikuchi E.

BMC Cancer. 2026 Mar 26. doi: 10.1186/s12885-026-15781-1. Online ahead of print. PMID: 41888732

 

Impact of radium-223 on bone imaging and biochemical markers with and without bone-modifying agents in bone-metastatic castration-resistant prostate cancer: results from the kyucog-1901 study.

Shiota M, Enokida H, Murakami Y, Kamoto T, Igawa T, Masumori N, Uemura H, Mitsunari K, Sumiyoshi T, Uemura H, Higashijima K, Tokunaga S, Isoda T, Ishigami K, Eto M.

Eur J Nucl Med Mol Imaging. 2026 Feb 10. doi: 10.1007/s00259-026-07807-4. Online ahead of print. PMID: 41665676

 

Biopsy Gleason score 5 + 4 predicts worse outcomes than 4 + 5 after robot-assisted radical prostatectomy: a nationwide multicenter cohort study.

Shimatani K, Kubota M, Yamamoto S, Mizuno K, Sumiyoshi T, Saito R, Ueda M, Iguchi R, Takahashi T, Yokozeki H, Iwamura H, Kohei N, Kurahashi R, Sekine Y, Sawada A, Negoro H, Akamatsu S, Kobayashi T, Goto T.

World J Urol. 2026;44(1):310.

 

Age-stratified outcomes of radical cystectomy for muscle-invasive bladder cancer: a nationwide multicenter study of 1867 patients in Japan.

Kawai T, Miki J, Taoka R, Saito R, Fukuokaya W, Matsui Y, Fujii Y, Hatakeyama S, Kawahara T, Matsuda A, Kato M, Sazuka T, Sano T, Urabe F, Kashima S, Naito H, Murakami Y, Miyake M, Daizumoto K, Matsushita Y, Nakayama M, Matsumoto T, Sugino Y, Shiga K, Yamaguchi N, Yamamoto S, Yasue K, Abe T, Nakanishi S, Hashine K, Fujii M, Nishihara K, Kobayashi K, Tatarano S, Wada K, Sekito S, Maruyama R, Nishiyama N, Nishiyama H, Kitamura H, Kume H; Japan Urological Oncology Group.

Jpn J Clin Oncol. 2026;56(4):475-483.

 

Genetically engineered human iPS cell-derived kidney organoid recapitulates an early stage of ALK fusion gene-associated renal tumorigenesis.

Noguchi G, Baba M, Ohtake S, Jikuya R, Mitome T, Kawamura S, Aomori K, Iribe Y, Nagasaka H, Wilan K, Funasaki S, Muraoka E, Fujii S, Tsuzuki T, Kato I, Furuya M, Nagashima Y, Nishizawa H, Kamba T, Kuraoka S, Kawagoe T, Mizuki N, Tatenuma T, Ueno D, Kawahara T, Ito H, Komeya M, Ito Y, Muraoka K, Uemura H, Tamura T, Ogawa T, Suda T, Yao M, Makiyama K, Nakagawa H, Shuch BM, Ricketts CJ, Schmidt LS, Linehan WM, Nishinakamura R, Hasumi H.

Mol Cancer Res. 2026;24(4):221-231.

 

Longitudinal Impact of Urinary Diversion on Health-Related Quality of Life After Radical Cystectomy: A Multicenter Study in Japan.

Yamada S, Sato M, Osawa T, Harabayashi T, Miki J, Kobayashi T, Hashine K, Kawashima A, Matsumoto T, Mochizuki T, Taoka R, Urabe F, Tatarano S, Sawada A, Kojima T, Takahashi A, Yokomizo A, Suekane S, Hashimoto K, Hashimoto Y, Yatsuda J, Morita K, Kobayashi K, Satake Y, Sazawa A, Matsui Y, Ito YM, Shimizu S, Fukuhara S, Nishiyama H, Kitamura H, Shinohara N; Japanese Urological Oncology Group.

Cancer Sci. 2026;117(3):739-748.

 

Effectiveness and Safety of Radium-223 for Bone-Metastatic Castration-Resistant Prostate Cancer: The KYUCOG-1901 Study.

Shiota M, Tatarano S, Kamba T, Kamaoto T, Igawa T, Masumori N, Uemura H, Mitsunari K, Sumiyoshi T, Uemura H, Higashijima K, Tokunaga S, Eto M.

Cancer Sci. 2026;117(2):501-510.

 

Validation of the 7-Item Quality of Life Disease-Specific Impact Scale in Patients Undergoing Radical Cystectomy for Bladder Cancer: A Cross-Sectional Study.

Shimizu S, Osawa T, Sato M, Yamada S, Harabayashi T, Miki J, Kobayashi T, Hashine K, Kawashima A, Matsumoto T, Mochizuki T, Taoka R, Urabe F, Tatarano S, Sawada A, Kojima T, Takahashi A, Yokomizo A, Suekane S, Hashimoto K, Hashimoto Y, Yatsuda J, Morita K, Kobayashi K, Satake Y, Sazawa A, Matsui Y, Ito YM, Nishiyama H, Kitamura H, Shinohara N, Fukuhara S; Japanese Urological Oncology Group.

Int J Urol. 2026;33(2):e70364.

 

Comparison of first-line immuno-oncology combinations with molecular targeted therapy in patients with advanced renal cell carcinoma undergoing hemodialysis: a real-world multicenter retrospective study.

Ueda K, Kurata H, Murakami Y, Minato A, Shiota M, Nakanishi S, Kiyoshima K, Inoue T, Kumagae H, Irie S, Noguchi M, Tatarano S, Matsuzaki H, Tokuda Y, Sawada A, Abe T, Oshiro Y, Harada S, Igawa T.

Int J Clin Oncol. 2026;31(1):160-171.

 

Comprehensive Histopathological and Biochemical Analyzes of Prostatic Amyloid Bodies (Corpora Amylacea) From Autopsy Samples From Japanese Patients.

Yatsuda J, Kanenawa K, Nomura T, Okada M, Masuda T, Misumi Y, Tasaki M, Ueda M, Ando Y, Kamba T.

Prostate. 2026;86(1):116-123.

 

 

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